About Gyan Pravah
Welcome to access “Gyan Pravah,” an Institutional Digital Repository of Pandit Deendayal Upadhyaya Central Library of Central University of Haryana. It comprises the institutional and faculty publications/documents i.e. papers, theses, dissertations, conference proceedings, ordinances, Annual Reports, Newsletters, Information Bulletins, media clipping, etc. to enhance the records dissemination and visibility of the University.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/1626| Title: | 2-Deoxy-D-Glucose: A Novel Pharmacological Agent for Killing Hypoxic Tumor Cells, Oxygen Dependence-Lowering in Covid-19, and Other Pharmacological Activities |
| Authors: | Singh, R Gupta, V Kumar, A Singh, K |
| Issue Date: | Mar-2023 |
| Abstract: | Te nonmetabolizable glucose analog 2-deoxy-D-glucose (2-DG) has shown promising pharmacological activities, including inhibition of cancerous cell growth and N-glycosylation. It has been used as a glycolysis inhibitor and as a potential energy restriction mimetic agent, inhibiting pathogen-associated molecular patterns. Radioisotope derivatives of 2-DG have applications as tracers. Recently, 2-DG has been used as an anti-COVID-19 drug to lower the need for supplemental oxygen. In the present review, various pharmaceutical properties of 2-DG are discussed. |
| URI: | http://hdl.handle.net/123456789/1626 |
| Appears in Collections: | School of Interdisciplinary & Applied Sciences |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2-Deoxy-D-Glucose_A_Novel_Pharmacological_Agent_fo.pdf | 455.34 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.