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http://hdl.handle.net/123456789/1626
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DC Field | Value | Language |
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dc.contributor.author | Singh, R | - |
dc.contributor.author | Gupta, V | - |
dc.contributor.author | Kumar, A | - |
dc.contributor.author | Singh, K | - |
dc.date.accessioned | 2024-10-14T05:30:01Z | - |
dc.date.available | 2024-10-14T05:30:01Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.uri | http://hdl.handle.net/123456789/1626 | - |
dc.description.abstract | Te nonmetabolizable glucose analog 2-deoxy-D-glucose (2-DG) has shown promising pharmacological activities, including inhibition of cancerous cell growth and N-glycosylation. It has been used as a glycolysis inhibitor and as a potential energy restriction mimetic agent, inhibiting pathogen-associated molecular patterns. Radioisotope derivatives of 2-DG have applications as tracers. Recently, 2-DG has been used as an anti-COVID-19 drug to lower the need for supplemental oxygen. In the present review, various pharmaceutical properties of 2-DG are discussed. | en_US |
dc.title | 2-Deoxy-D-Glucose: A Novel Pharmacological Agent for Killing Hypoxic Tumor Cells, Oxygen Dependence-Lowering in Covid-19, and Other Pharmacological Activities | en_US |
Appears in Collections: | School of Interdisciplinary & Applied Sciences |
Files in This Item:
File | Description | Size | Format | |
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2-Deoxy-D-Glucose_A_Novel_Pharmacological_Agent_fo.pdf | 455.34 kB | Adobe PDF | View/Open |
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